By P. Dawson PhD, MRCP, FRCR (auth.), P. Dawson, W. Clauss (eds.)
For all that new non-X-ray applied sciences corresponding to MR and ultrasound and its numerous manifestations have made an incredible effect in recent times at the perform of clinical imaging, using X-rays and X-ray contrast-enhancing brokers has retained an incredible place on the center of the method. certainly, with its widespread necessities for prime overall dose regimes, CT has elevated using distinction brokers. Even helical/spiral CT which, it was once at first argued, may still lessen distinction in addition to radiation rather a lot, may very well require simply as a lot or extra of either end result of the strength it bargains for multi-phase scanning.
Iodinated intravascular X-ray distinction brokers, specially the extra lately constructed non-ionic brokers, proceed accordingly to play a pivotal position in scientific imaging.
those succinct and authoritative articles, initially showing within the magazine Advances in X-ray Contrast, variety sufficiently commonly for his or her compilation during this quantity to be thought of a mini-textbook at the water-soluble iodinated X-ray distinction brokers and their purposes. each one is written via an stated and skilled specialist within the box. They usefully disguise the developmental heritage of the brokers; outlined danger elements, techniques to prophylaxis and, finally, of the therapy of difficult reactions; the attention-grabbing topic of intended behind schedule reactions to distinction brokers; the $64000 organ-specific toxicities, cardiac toxicity, neurotoxicity and nephrotoxicity and high-dose toxicity as encountered in advanced tactics; the occasionally targeted situations and low severe stipulations to which distinction brokers should be uncovered in Interventional Radiology; the specified, in numerous methods, case of paediatric radiology; the arguable topic of thromboembolic phenomena in scientific angiography; and the proper position of distinction brokers. As regards the practicalities of distinction management regimes and imaging protocols it truly is purely within the quarter of CT that there's debate and controversy, and articles are integrated which conceal CT of the liver, spleen and pancreas, and protocols for the recent spiral/helical expertise or even for the less extensively to be had electron-beam CT know-how visualization. Pulmonary embolus prognosis and protocols for distinction management with this know-how also are discussed.
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For all that new non-X-ray applied sciences resembling MR and ultrasound and its a number of manifestations have made a massive effect in recent times at the perform of clinical imaging, using X-rays and X-ray contrast-enhancing brokers has retained an incredible place on the middle of the method. certainly, with its widespread necessities for top overall dose regimes, CT has elevated using distinction brokers.
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Additional info for Advances in X-Ray Contrast: Collected Papers
Chemotoxic reactions are due to specific physicochemical effects of the CM and, unlike anaphylactoid reactions, are directly dependent upon its dose, concentration, osmolality, potential calcium ion binding and nature of the associated cation . g. intravenous vs intraarterial) therefore play a significant role in chemotoxicity . Chemotoxic reactions, particularly those due to the osmolality of the injected CM, usually affect the central nervous system, respiratory tract, cardiovascular system and kidneys and, in general, are similar to those seen in adults [1,2).
European Radiology 1995; 5: SIOIS106. Chronos NAF, Goodall AH, Wilson OJ, Sigwart Y, Buller NP. Profound platelet degranulation is an important side effect of some types of contrast media used in interventional cardiology. Circulation 1993; 88: 2044-2045. Dawson P et al. Unpublished data. P. ), Advances in X-Ray Contrast: Collected Papers. 29-33 © 1998 Kluwer Academic Publishers. Delayed reactions to intravenous injections of urographic contrast media Peter Davies, FRCR, DM Nottingham City Hospital, Hucknall Road, Nottingham, NG51PB, UK INTRODUCTION There are two fundamental aspects to the study of reactions, either acute or delayed: 1.
It must therefore be presumed that such patients are also at risk of delayed reactions. References 1. 2. 3. 4. 5. Mikkonen R. Kontkanen T, Kivisari L. Acute and late adverse reactions to low-osmolal contrast media. Acta Radiol. 1995; 36: 72-76. Mikkonen R, Kontkanen T, Kivisari L. Late and acute adverse reactions to iohexol in a pediatric population. Pediatr Radiol. 1995; 25: 350--352. Stovsky MD, Sefte! AD, Resnick MI. Delayed hypersensitivIty reactIOn after infusion of nonionic intravenous contrast material for an excretory urogram: a case report and review of the literature.
Advances in X-Ray Contrast: Collected Papers by P. Dawson PhD, MRCP, FRCR (auth.), P. Dawson, W. Clauss (eds.)