By F. Dickens, W. J. Whelan, P. J. Randle
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And Berson, S. A. (1963). Nature, Lond. 199,784. Glick, S. , Roth, J. and Lonergan, E. T. (1964). / . clin. Endocr. Metab. 24, 501. Glick, S. , Yalow, R. S. and Berson, S. A. (1965). Recent Prog. Horm. Res. 21,241. Goetz, F. C. (1965). In "On the Nature and Treatment of Diabetes" (B. S. Leibel and G. A. Wrenshall, eds), pp. 181-193, Excerpta Medica, Amsterdam. 48 C. N . HALES Graber, A. , Wood, F. C. Jr. and Williams, R. H. (1966). Diabetes 15, 515. Greenberg, E. (1965). Diabetes 14, 43. Greenwood, F.
F. and Burnham, C. (1965). Diabetes 14, 473. , Holdsworth, C. D. and Turner, D. S. (1964). Lancet ii, 20. Mclntyre, N , Holdsworth, C. D. and Turner, D. S. (1965). / . clin. Endocr. Metab. 25, 1317. , Turner, D. S. and Holdsworth, C. D. (1965). Diabetologia 1, 73. Maclean, N. and Ogilvie, R. F. (1955). Diabetes 4, 367. Maclean, N. and Ogilvie, R. F. (1959). Diabetes 8, 83. , Howarth, N. and Greenwood, F. C. (1965). Nature, Lond. 208, 686. Martin, J. M. (1966). Diabetes 15, 359. Meade, R. C , Stiglitz, R.
V. GLUCAGON The evidence that glucagon can cause an increase in insulin secretion has been cited. If this effect is involved in the physiological regulation of insulin secretion it is important to determine whether diabetics have any abnormality of glucagon metabolism. There is, as yet, very little information available concerning the regulation of plasma glucagon concentrations in diabetes. Schalch (1966) found that obese diabetics had normal overnight fasting glucagon concentrations. After 100 g oral glucose plasma glucagon levels rose significantly and to the same extent in both normals and diabetics.
Carbohydrate Metabolism. And its Disorders by F. Dickens, W. J. Whelan, P. J. Randle